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Staffan Eriksson Selected Research

Thymidine

1/2022Structural and functional analysis of human thymidylate kinase isoforms.
2/2015Breast and prostate cancer patients differ significantly in their serum Thymidine kinase 1 (TK1) specific activities compared with those hematological malignancies and blood donors: implications of using serum TK1 as a biomarker.
10/2014Properties of cellular and serum forms of thymidine kinase 1 (TK1) in dogs with acute lymphocytic leukemia (ALL) and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker.
1/2013Homogeneous assay for real-time and simultaneous detection of thymidine kinase 1 and deoxycytidine kinase activities.
1/2012Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2).
5/20103'-(1,2,3-Triazol-1-yl)-3'-deoxythymidine analogs as substrates for human and Ureaplasma parvum thymidine kinase for structure-activity investigations.
11/2008Thymidine kinase 1 as a molecular target for boron neutron capture therapy of brain tumors.
3/2008Synthesis and biological evaluation of inhibitors of thymidine monophosphate kinase from Bacillus anthracis.
10/2006Hydrophilically enhanced 3-carboranyl thymidine analogues (3CTAs) for boron neutron capture therapy (BNCT) of cancer.
9/2006Preparation and biological evaluation of 10B-enriched 3-[5-{2-(2,3-dihydroxyprop-1-yl)-o-carboran-1-yl}pentan-1-yl]thymidine (N5-2OH), a new boron delivery agent for boron neutron capture therapy of brain tumors.
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Staffan Eriksson Research Topics

Disease

29Neoplasms (Cancer)
01/2022 - 05/2002
8Breast Neoplasms (Breast Cancer)
08/2021 - 02/2004
4Infections
11/2019 - 01/2008
4Brain Neoplasms (Brain Tumor)
11/2008 - 09/2004
3Lymphoma (Lymphomas)
12/2021 - 09/2004
3Adenocarcinoma
06/2017 - 05/2005
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2014 - 06/2002
3Glioma (Gliomas)
11/2013 - 09/2004
2Mitochondrial Diseases (Mitochondrial Disease)
01/2022 - 04/2020
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 01/2022
2Stroke (Strokes)
10/2021 - 12/2019
2Virus Diseases (Viral Diseases)
11/2019 - 01/2013
2Prostatic Neoplasms (Prostate Cancer)
01/2019 - 02/2015
2Adenocarcinoma of Lung
01/2014 - 04/2012
2Renal Cell Carcinoma (Grawitz Tumor)
06/2010 - 06/2009
2Anthrax
03/2008 - 12/2006
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
03/2006 - 03/2003
2Muscular Diseases (Myopathy)
03/2005 - 02/2003
2Leukemia
03/2003 - 06/2002
1Microcephaly
01/2022
1Genomic Instability
01/2022
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2021
1Hodgkin Disease (Hodgkin's Disease)
01/2021
1Cholelithiasis
01/2021
1Cholangitis
11/2020
1Pancreatitis
11/2020
1Hemorrhage
11/2020
1Bacterial Infections (Bacterial Infection)
11/2019
1Pain (Aches)
04/2019
1Knee Osteoarthritis
04/2019
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
02/2015
1Hematologic Neoplasms (Hematological Malignancy)
02/2015
1Herpes Simplex
01/2012
1Lesch-Nyhan Syndrome (Choreoathetosis Self Mutilation Hyperuricemia Syndrome)
12/2010
1Gout
12/2010
1Opportunistic Infections (Opportunistic Infection)
05/2010
1Colorectal Neoplasms (Colorectal Cancer)
11/2009
1Hyperplasia
11/2009
1Noninfiltrating Intraductal Carcinoma (DCIS)
11/2009
1Dementia (Dementias)
05/2008
1Mobility Limitation (Difficulty Walking)
04/2007

Drug/Important Bio-Agent (IBA)

18thymidine kinase 1IBA
12/2021 - 09/2004
14ThymidineIBA
01/2022 - 08/2002
10NucleosidesIBA
01/2013 - 03/2003
9Biomarkers (Surrogate Marker)IBA
12/2021 - 01/2014
7EnzymesIBA
01/2022 - 09/2004
6Proteins (Proteins, Gene)FDA Link
01/2018 - 06/2010
5DNA (Deoxyribonucleic Acid)IBA
01/2022 - 06/2009
4Deoxycytidine KinaseIBA
01/2013 - 08/2004
4Thymidine KinaseIBA
05/2010 - 09/2004
3dTMP kinaseIBA
01/2022 - 03/2008
3thymidine 5'-triphosphate (thymidine triphosphate)IBA
01/2022 - 08/2010
3Anti-Bacterial Agents (Antibiotics)IBA
11/2020 - 06/2006
3NucleotidesIBA
05/2010 - 03/2003
3Antiviral Agents (Antivirals)IBA
01/2010 - 12/2004
3BoronIBA
09/2006 - 08/2002
3DeoxycytidineIBA
03/2006 - 03/2003
3CladribineFDA LinkGeneric
03/2006 - 01/2003
2Thymidine Monophosphate (TMP)IBA
01/2022 - 03/2008
2AntibodiesIBA
02/2015 - 05/2005
2Enzyme Precursors (Zymogens)IBA
10/2014 - 06/2009
2Phosphotransferases (Kinase)IBA
01/2012 - 06/2002
2Reverse Transcriptase InhibitorsIBA
03/2007 - 03/2005
2Biological ProductsIBA
09/2006 - 02/2005
2Messenger RNA (mRNA)IBA
03/2006 - 08/2004
2fludarabineIBA
03/2006 - 01/2003
2ProdrugsIBA
03/2006 - 06/2002
2deoxyguanosine kinaseIBA
03/2006 - 03/2003
2Monoclonal AntibodiesIBA
05/2005 - 10/2004
2Mitochondrial DNA (mtDNA)IBA
01/2005 - 02/2003
2Clofarabine (Clolar)FDA Link
03/2003 - 01/2003
29-arabinofuranosylguanineIBA
06/2002 - 05/2002
1Amino AcidsFDA Link
01/2022
1Protein Isoforms (Isoforms)IBA
01/2022
1Leukocyte L1 Antigen Complex (Calgranulin)IBA
01/2021
1LipocalinsIBA
11/2019
1Prostate-Specific Antigen (Semenogelase)IBA
01/2019
1DeoxyribonucleotidesIBA
01/2018
1ferric oxide (iron oxide)IBA
01/2016
1Peptides (Polypeptides)IBA
02/2015
1AN 3IBA
10/2014
1Dihydrotachysterol (AT 10)IBA
04/2012
1Nucleoside Transport Proteins (Nucleoside Transporter)IBA
01/2012
1O-(18F)fluoromethyl-L-tyrosineIBA
01/2012
1Protease Inhibitors (Protease Inhibitor)IBA
08/2011
1Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)IBA
12/2010
1deoxyribonucleoside kinasesIBA
01/2010
1Proliferating Cell Nuclear Antigen (PCNA)IBA
11/2009
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
05/2008
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
05/2008
1Phosphates (Orthophosphate)IBA
03/2008

Therapy/Procedure

6Boron Neutron Capture Therapy
02/2013 - 08/2002
4Therapeutics
04/2020 - 11/2009
4Drug Therapy (Chemotherapy)
01/2015 - 12/2004
2Neoadjuvant Therapy
07/2014 - 09/2013
1Secondary Prevention
10/2021
1Lymph Node Excision (Lymph Node Dissection)
08/2021
1Cholecystectomy
01/2021
1Tourniquets
04/2019
1Injections
11/2008